The Marcogliese lab
The Marcogliese Lab aims to be an inclusive, diverse, and dynamic group of enthusiastic scientists with expertise across a variety of disciplines, including molecular & cell biology, genetics, and biochemistry.
Paul C Marcogliese, PhD
Danielle M Pascual, BSc
Catherine D Bland
Paul received both a BA and BSc from Carleton University. He completed his Ph.D. in Neuroscience in 2016 in the Department of Cellular & Molecular Medicine at the University of Ottawa, under the supervision of Dr. David S. Park. There he studied mouse, fruit fly, and cellular models of Parkinson's disease. Paul completed his postdoctoral training with Dr. Hugo J Bellen at Baylor College of Medicine in 2022. During his postdoc, Paul studied rare forms of neurological disorders using Drosophila.
Outside the lab, Paul spends his time with his family, developing scientific outreach, and finding creative outlets.
Danielle received her BSc in Psychology with a minor in Biological Sciences from the University of Manitoba in Spring 2022. She is broadly interested in neuroscience, neurodegeneration, and disorders of the brain. Her current project in the Marcogliese lab continues work on the underlying causes of IRF2BPL-related neurological conditions like NEDAMSS, ASD, and parkinsonism. She will examine IRF2BPL function in flies, mice, and human cells.
Outside the lab, Danielle enjoys playing ultimate frisbee, instruments and spending time with her family and dog, Simba.
Alondra received her BSc in Biochemistry from the University of Winnipeg in 2023. At the moment she is interested in pursuing medicine. As the labs' first research technician, Alondra is involved in multiple lab projects examining the cellular and molecular mechanisms underlying neurological disease.
Outside the lab, Alondra enjoys spending time outdoors with her dog Dexter, watching the latest true crime documentaries, and have recently obtained a record player and is excited to start a vinyl collection.
Catherine is a third-year biochemistry student from the University of Manitoba. She is interested in the researching process, especially in investigating the fundamental biology of neurological disorders. As a Co-op student in the Marcogliese lab, Catherine is leading a screen examining the role of Wnt in the postnatal brain. She will employ adult-specific manipulation of Wnt components in flies to assess their role in long-term neuronal function and maintenance.
Outside the lab, Catherine finds joy in reading books, drawing, and taking care her sister.
Harsimran is a fourth year psychology student from University of Manitoba. She is really interested in statistical analysis and different neurological processes that cause neurological disorder, for instance, significance of dopamine in Parkinson’s disease.
In her leisure time, Harsimran likes to cook and take walks in the park near her Winnipeg home.
Adedayo is a fourth year Genetics student from the university of Manitoba. He is passionately interested in determining the causes of neurological disorders. As an honours student in the Marcogliese Lab, Adedayo will develop tools for genes related to Wnt signalling in flies and determine their role in neurodegeneration.
Outside the lab, Adedayo enjoys modelling, playing musical instruments and keeping fit.
Mahkam is a fourth year Genetics student with plans to pursue Precision Medicine and discovering the underlying causes of incurable and rare neurological diseases.
As an Honours student in the Marcogliese lab, Mahkam is leading a targeted screen in Drosophila for MECP2 modifiers related to Rett syndrome. This project is co-supervised by Dr. Galen Wright and will identify MECP2 modifiers, primarily involved in DNA-damage response, in vivo.
Outside the lab, Mahkam enjoys playing Iranian traditional instruments, reading poems, and late night drives.